Most members of the U.S. Food and Drug Administration (FDA) advisory group believenftgamecoin, Novo Nordisk (NVOnftgamecoin.US) The benefits of weekly injections of insulin icodec do not outweigh the risks.
Among the 11 voting members at the Endocrine and Metabolic Drugs Advisory Committee meetingnftgamecoin, 7 members disagreed that the benefits outweigh the disadvantages, while 4 members agreed.
Briefing documents provided by FDA scientists showed that in a pivotal trial, weekly insulin icodec was associated with hypoglycemia compared to Novo Nordisk's daily injection of Tresiba(insulin degludec). Several expert group members expressed concern about this.
Novo Nordisk mentioned that using blood sugar monitoring equipment when prescribing the drug is a way to reduce the risk of hypoglycemia.
Several members said that insulin icodec may be suitable for some patients, but Novo Nordisk needs to clarify which groups these patients belong to.
It is worth mentioning that Novo Nordisk competitor Lilly earlier this monthnftgamecoin.US) reported positive data from two phase III trials of its weekly injection of insulin efsitora.